Detalles de la búsqueda
1.
Novel Pyrimidine-5-Carbonitriles as potential apoptotic and antiproliferative agents by dual inhibition of EGFRWT/T790M and PI3k enzymes; Design, Synthesis, biological Evaluation, and docking studies.
Bioorg Chem;
145: 107185, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38350273
2.
Synthesis of novel pyrimido[4,5-b]quinoline derivatives as dual EGFR/HER2 inhibitors as anticancer agents.
Arch Pharm (Weinheim);
357(3): e2300513, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38148301
3.
New Phenylthiazoles: Design, Synthesis, and Biological Evaluation as Antibacterial, Antifungal, and Anti-COVID-19 Candidates.
Chem Biodivers;
20(11): e202301143, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37857580
4.
Synthesis and biological evaluation of halogenated phenoxychalcones and their corresponding pyrazolines as cytotoxic agents in human breast cancer.
J Enzyme Inhib Med Chem;
37(1): 189-201, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34894967
5.
Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines.
Bioorg Med Chem Lett;
41: 127987, 2021 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33771586
6.
Design, Synthesis, and Antipoliferative Activities of Novel Substituted Imidazole-Thione Linked Benzotriazole Derivatives.
Molecules;
26(19)2021 Oct 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34641526
7.
Design and synthesis of pyrazolo[3,4-d]pyrimidinone derivatives: Discovery of selective phosphodiesterase-5 inhibitors.
Bioorg Med Chem Lett;
30(16): 127337, 2020 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32631538
8.
Design, synthesis, and cytotoxic screening of novel azole derivatives on hepatocellular carcinoma (HepG2 Cells).
Bioorg Chem;
101: 103995, 2020 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-32569897
9.
New benzenesulfonamide scaffold-based cytotoxic agents: Design, synthesis, cell viability, apoptotic activity and radioactive tracing studies.
Bioorg Chem;
96: 103577, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31978683
10.
Synthesis and biological evaluation of pyrazolone analogues as potential anti-inflammatory agents targeting cyclooxygenases and 5-lipoxygenase.
Arch Pharm (Weinheim);
353(4): e1900308, 2020 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-32031284
11.
Design, synthesis, and biological evaluation of new pyrazoloquinazoline derivatives as dual COX-2/5-LOX inhibitors.
Arch Pharm (Weinheim);
353(11): e2000027, 2020 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-32696514
12.
A new class of diamide scaffold: Design, synthesis and biological evaluation as potent antimitotic agents, tubulin polymerization inhibition and apoptosis inducing activity studies.
Bioorg Chem;
84: 399-409, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30551066
13.
Novel indolyl 1,2,4-triazole derivatives as potential anti-proliferative agents: in silico studies, synthesis, and biological evaluation.
RSC Med Chem;
15(1): 293-308, 2024 Jan 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38283222
14.
Recent Modifications of Anti-dementia Agents Focusing on Tacrine and/or Donepezil Analogs.
Med Chem;
19(4): 311-324, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36043761
15.
Early electrophysiological study variants and their relationship with clinical presentation and outcomes of patients with Guillain-Barré syndrome.
Sci Rep;
13(1): 14000, 2023 08 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-37634022
16.
Synthesis of novel pyrimido[4,5-b]quinolines as potential anticancer agents and HER2 inhibitors.
Chem Biol Drug Des;
102(5): 996-1013, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37527951
17.
Design, synthesis, and biological evaluation of new pyrimidine-5-carbonitrile derivatives as novel anti-cancer, dual EGFRWT/COX-2 inhibitors with docking studies.
RSC Adv;
13(46): 32296-32320, 2023 Oct 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-37928843
18.
The Anti-MRSA Activity of Phenylthiazoles: A Comprehensive Review.
Curr Pharm Des;
28(43): 3469-3477, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36424796
19.
Effects of transcranial direct current stimulation in pain and opioid consumption after spine surgery.
Eur J Pain;
26(7): 1594-1604, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35634761
20.
Pre- and in-hospital delays in the use of thrombolytic therapy for patients with acute ischemic stroke in rural and urban Egypt.
Front Neurol;
13: 1070523, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36742046